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The risk fell significantly among patients in the Treating to New Targets trial who received atorvastatin at 80 mg/day, as compared with those
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In the other trials, there was a slightly increased risk when an 80-mg dose was compared with lower doses (10-mg atorvastatin in TNT, 20-mg
s post-hoc analysis of patients enrolled in the randomized, double-blind Treating to New Targets (TNT) trial has revealed that high-dose atorvastatin after CABG
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The Treating to New Targets (TNT) study demonstrated that intensive atorvastatin therapy to achieve low-density lipoprotein cholesterol concentrations well
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This study was a large randomised comparison of low and high doses of atorvastatin in patients with established coronary disease, to investigate whether there
Atorvastatin reduces the risk of cardiovascular events in patients with carotid heart disease (a post hoc analysis of the treating to new targets [TNT] study).
For example, in the Treating to New Target (TNT) trial, patients taking atorvastatin 80mg. (mean LDL-C level 77mg/dl) had a 28% CV event rate compared with a
Atorvastatin is used for the treatment of high cholesterol and triglyceride levels. to New Targets (TNT) study, which has already shown that patients treated with
Data from the Treating to New Targets (TNT) study demonstrated that intensive lipid-lowering therapy with 80 mg/d of atorvastatin significantly
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0.74 (0.58,0.94). TNT (10001). Atorvastatin 80. 77. 0.72 (0.52,0.98). A to Z (4497). Simvastatin 80. 63. 0.54 (0.34,0.85). PROVE-IT (4162). Atorvastatin 80. 62
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The TNT study was ideal for testing this hypothesis, because 4654 patients with prior CABG were randomized to high- or low-dose atorvastatin.
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