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For the study, Juurlink's team collected data on 39736 patients treated with Avandia or Actos between April 2002 and March 2008.
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Discontinue Actos (pioglitazone) or Avandia (rosiglitazone).5 Maintain or consider adding metformin. If hypoglycemia develops, consider reducing dose or
They used Metformin, Avandia or Actos. Drug Lowers Conversion To Type 2 Diabetes By 81% In Multicenter Study June 11, 2008 In a research study of
The FDA had already concluded a new study that showed a disproportionate risk for those patients using Actos for Type-2 diabetes versus Avandia or other
The figures break down to 96 Avandia, versus 121 Actos patients suffering a heart attack and 265 Avandia and 243 Actos patients suffering from heart failure,
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Don't take either Avandia or Actos. These drugs do not provide anywhere near enough benefit to outweigh their dangerous side effects.
The study involved 227571 Medicare patients, average age 74, who started on Actos or Avandia from July 2006 through June 2009 and were
Plasma TG were higher in FH vs. to prime the bicarbonate pool. 001, whereas fasting plasma NEFA were not significantly avandia side effects different between
In clinical trials, Avandia (rosiglitazone maleate) and ACTOS "Avandia can be used alone or with [Glucophage] to produce good glucose
Drugs known as TZD's (trade names Actos and Avandia) directly attack the problem, TZD's help the type 2 diabetic make better use of the insulin he or she still
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I was on Avandamet and have been switched to ActosMet, but now I don't or might not happen later on down the road with this class of drugs.
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The analysis in the journal Diabetes Care projected that one in every 50 patients who takes Avandia or Actos over a 26-month period would be hospitalized for
Mortality in Observational Studies of AVANDIA Compared to ACTOS: Three observational studies in elderly diabetic patients (age 65 years and older) found that
effect of some diabetes medications such as Avandia or Actos . Some people have it when first beginning on insulin Side effects of Januvia? Anyone?
Log in or create a free account for complete access risk of congestive heart failure with either pioglitazone (Actos) or rosiglitazone (Avandia),
Avandia and pioglitazone (Takeda's Actos) are the only marketed may work to preserve and/or enhance beta-cell function, and thus to help
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Bloomberg News FDA Commissioner Margaret Hamburg, above, says the agency is reassessing the trial involving Avandia versus Actos.
Glaxo has also drawn fire for conducting a study¾currently halted by the FDA¾that compares the risks of Avandia versus its competitor, Actos.
Prominent Harvard cardiologist Dr. Om Ganda, who addressed the Actos-vs.- Avandia cardiovascular risk issue, seemed to disappoint the
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Actos is most definitely a superior lipid-modifying agent when compared to Avandia (although they are equally effective in terms of glycemic control) [see Image
For the FDA, the Avandia decision is likely to be seen as a hallmark case . of the RECORD trial, and about the risks of Avandia versus Actos.
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The analysis by Graham found that Actos had roughly a 25% lower risk of heart attack versus active comparators, including Avandia. Graham
risk of AVANDIA and ACTOS® (pioglitazone, another thiazolidinedione), but in a separate trial, ACTOS (when compared to placebo) did not show an increased
Does anyone know which of the two is healthier, more effective, how they work differently? Any opinions are welcomed.
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The study involved 227571 federal health program patients, average age 74, who started on Actos or Avandia from July 2006 through June
These are typically ejaculatory dysfunction, especially delayed ejaculation or Sertraline use should be avoided or alternatives considered with multiple
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At a cost of $5.87 for each 30-mg tablet, a 1-month supply of Actos is approximately $176. Slightly less expensive, Avandia costs $3.83 per tablet, or $115 per
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News on Actos, Pioglitazone (generic) continually updated from thousands of effects of pioglitazone or gliclazide addition to failing metformin monotherapy and with increased cardiovascular risk, as recently reported for rosiglitazone.
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People taking Avandia's rival Actos, or pioglitazone, from Japan's Takeda Pharmaceutical, didn't show up in the analysis. Today []
The study analyzes Medicare records for 227571 patients who started treatment with Avandia or Actos between July 2006 and June 2009.
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The trial involved comparing the health benefits of Avandia versus other competing drug, such Actos produced by Takeda Pharmaceuticals.
GlaxoSmithKline's diabetes drug Avandia faces renewed reports of cardiac risks, while Takeda's Actos appears to reduce such risks. as it draws from four studies that followed more than 14000 patients for a year or more.
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Actos and Avandia are both good medications. Many of the FDA panelists who voted to pull Avandia or severely restrict it, mentioned that they did so because
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In all of these analyses, the Avandia and the Actos hazard ratios (HR of Avandia versus other oral anti-diabetic medicines, including Actos. 1.
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cardiovascular outcomes for Avandia versus Actos (the TIDE study). The FDA later suspended that study due to safety concerns about the risks
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likely to switch patients to Takeda's Actos than to Byetta or Januvia.
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Actos vs. Avandia I will agree that there are no studies that undeniably show that Avandia causes significant CV events, but there is data to
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Titrate in increments of rosiglitazone 4 mg and/or metformin 500 mg po daily. ACTOS is indicated as an adjunct to diet and exercise to improve glycemic
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found no statistically significant increase in emergency department visits or hospitalization for heart failure in patients treated with AVANDIA compared to ACTOS
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Both Avandia and Actos carry warnings that the drugs may cause or exacerbate congestive heart failure, but Actos does not appear to cause
HbA1c 7% or greater three months later. Add rosiglitazone [Avandia] or pioglitazone [Actos] (expected decrease in HbA1c 0.5-1.4%) or sulfonylurea ( expected
The expression profile of key drug metabolism genes should be different in cells treated with Rezulin versus those treated with Avandia and Actos.
In 2007 a major study was concluded that compared health risks in persons taking either Actos or another diabetes drug Avandia. This study was done using
Article title, keywords or abstract; Article title; Publication title; Author Objectives : Pioglitazone hydrochloride (Actos††) and rosiglitazone
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Participants Outpatients aged 66 years and older who were started on rosiglitazone or pioglitazone between 1 April 2002 and 31 March 2008.
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Avandia, or rosiglitazone, is one of a new class of anti-diabetes drugs approved for marketing by the FDA in 1999. It, and its competitor, Actos
Avandia and Actos help diabetics use their own insulin better by hitting a Fibrates like gemfibrozil, which lower triglycerides and raise HDL, or
The 33-month study looked at over 36000 patients averaging 54 years of age and 14 months of diabetes treatment with Actos or Avandia. The subjects were
Consumer ratings reports for ACTOS. Includes patient rankings
Differential effects on lipids with pioglitazone vs rosiglitazone agents, pioglitazone (Actos®, Takeda/Lilly) and rosiglitazone (Avandia®,
Researchers who analysed data on 78000 patients who took Avandia or Actos to treat type II diabetes found that it increased the risk of heart failure by up to 100
Patients and their healthcare providers began to immediately limit their options by automatically changing Avandia to Actos, or canning the TZD
The FDA May Halt The Avandia Safety Study the trial involving Avandia versus Actos “based on expert input and our own analysis,” the paper
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Last year, Avandia had $521 million in sales in the United States, compared to market leader Actos with $3.4 billion, according to data provided
Merck's Januvia generated $1.9 billion in global sales. Neither drug poses the same kind of cardiac risks as Avandia or Actos, Wijma says.
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The labels for both Avandia and Actos contain warnings that the drugs may cause or exacerbate congestive heart failure in certain patients. Some studies, but
Mortality in Observational Studies of Avandia Compared to ACTOS: Three observational studies in elderly diabetic patients (age 65 years and older) found that
DREAM {rosiglitazone vs placebo in pre-diabetes without CV disease; 0.5% vs 0.1%; NNH=250/3yrs}5 o. PROactive {pioglitazone ACTOS vs
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Actos bladder cancer lawsuits filed in California state court will be cancer cases in patients receiving Actos versus comparators," the FDA wrote in its thiazolidinediones -- pioglitazone and rosiglitazone (Avandia) -- are
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In the new analysis, researchers looked at the results of 16 studies that involved 810000 users of Avandia or Actos (pioglitazone), a similar
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CHICAGO (Reuters) - GlaxoSmithKline's diabetes drug Avandia was no generically as rosiglitazone, or Takeda Pharmaceutical Co's Actos,
Avandia (rosiglitazone); Actos (pioglitazone). As of May 21, 2007, the FDA has issued a safety alert regarding the possibility of heart attacks or other fatal
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Both rosiglitazone and pioglitazone are indicated either as monotherapy or in Avandia [rosiglitazone maleate; GlaxoSmithKline] and Actos5 [pioglitazone
The VA has changed me from Avandia to Actos because my good cholesterol was very low, >4 offline Yellowboat, Re: Avandia vs Actos, #11, [url], [-]. Ok I have
The study, said the Heart, looked at fracture risk in over 84000 patients who received Avandia (rosiglitazone) or Actos (pioglitazone) over a
The other drug in the class, Actos, made by Takeda, has appeared safe, in part because it seems to affect a different set of genes than either Rezulin or Avandia.
In this analysis, approximately 4 percent of patients taking either drug -- sold as Avandia and Actos -- suffered a heart attack, heart failure, both or died over a
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Furthermore, discontinuation or dose reduction of AVANDIA must be considered. of AVANDIA and ACTOS® (pioglitazone, another thiazolidinedione), but in a
Rosiglitazone is an antidiabetic drug in the thiazolidinedione class of drugs. . take Actos (pioglitazone) or other pioglitazone-containing medicines for medical
NEW ORLEANS -- Compared with glipizide, rosiglitazone (Avandia) did patients treated with pioglitazone (Actos) versus glimepiride, which,
Both Avandia and Actos have proven benefit of improving glycemic control in type 2 diabetes, but at the expense of known side effects of edema and/or heart
with Actos versus Avandia correspond with associated differences in hepatic gene expression. He queried the DrugMatrix database and compared hepatic gene
Drugs or pills are for sale in different forms such as injections right ACTOS, ALDARA, AMARYL, ANUCORT-HC, AVANDIA, and so on are
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Recent diabetes medication added. If you take insulin or an insulin secretagogue like Diabeta and then start taking Avandia, Actos or Glucuphage (metformin)
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Actos and Avandia (Glitazones). Thiazolidinediones or glitazones are the first class of medication designed to reverse the basic problem in
Rosiglitazone (Avandia) and pioglitazone (Actos) are approved as adjuncts risk reduction with AVANDIA or any other oral antidiabetic drug.
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A new study finds that patients taking either of the diabetes drugs Avandia or Actos face twice the risk of developing heart failure compared to
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If you or loved one suffered a heart attack or been diagnosed with bladder The figures break down to 96 Avandia, versus 121 Actos® patients suffering a heart
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Compared to controls, individuals taking Avandia or Actos had more than double the risk of fractures, with the risk with Actos being slightly
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Thiazolidinediones or TZDs act by activating PPARs (peroxisome Rosiglitazone (Avandia), which was put under selling restrictions in the US and the sale of the diabetes drug Actos after a study suggested the drug, also known as
Actos 45 mg Tablets; Actos Alternatives; Actos and Blood Sugar; Actos and Actoplus Met alternatives may include other diabetes medicines or lifestyle
“We have had serious doubts about the safety of Avandia for a number lose any weight you had put on as a result of taking Avandia or Actos.
I know what you must be wondering, first Avandia, now Actos, now Continue taking Actos, or other pioglitazone-containing medications,
The BBC said that Avandia, also known as rosiglitazone, was have said that “a drug to treat diabetes, Actos, would be a 'sensible alternative' to one the results of RCTs of rosiglitazone versus another drug or placebo, and
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In that study, conducted in 1999, GSK found that Avandia had a higher risk of causing heart problems compared to its chief rival, Actos.
In Canada, Actos®, in addition to diet and exercise, can be used alone to control blood sugar. Avandia® can be used alone or in combination with either
Two Studies Suggest Diabetes Drug Avandia Increases Risk Of Heart Medicare beneficiaries taking either Avandia or Actos [pioglitazone
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Some people gain weight on Avandia or Actos, but that has not been my experience, I have lost 30 to 40 pounds over the last seven years. As far as heart
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A) Avandia and Actos are both in the same class of medications, taken Avandia for a longer period of time (in the past or still currently using)?
Rosiglitazone is sold as a single-ingredient product under the brand name medicines (Actos, Actoplus Met, Actoplus Met XR, or Duetact).
embattled diabetes drug Avandia on the market, scrutiny of the drug has opened the door to same kind of cardiac risks as Avandia or Actos, Wijma says.
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Dr. David Graham and Dr. Kate Gelperin of the FDA say that continuing a study of Avandia versus another diabetes drug, Actos, would be
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First the painkiller Vioxx; now the diabetes drug Avandia. higher risk of heart attack for those taking Avandia compared to people taking $2.6 billion for Actos , according to IMS Health, a healthcare information company.
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The FDA warning against Actos came after two European countries banned the drug Multaq (dronedarone) was found to increase the risk of death or serious Avandia, one of the pharmaceutical company's most widely distributed drugs,
GlaxoSmithKline has reportedly settled around 700 Avandia lawsuits. telling him that the agency is reassessing the Avandia versus Actos
Rosiglitazone is widely used to treat patients with type 2 diabetes rosiglitazone (Avandia, GlaxoSmithKline) and pioglitazone (Actos, Takeda). .. Glycemic durability of rosiglitazone, metformin, or glyburide monotherapy.
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Explains the medication rosiglitazone (Avandia), a drug used for the treatment of type II The other member of this class is pioglitazone (Actos). Patients with type 2 diabetes cannot make enough insulin or are resistant to the effects of
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At this point, the patient can benefit both by reducing insulin resistance with insulin sensitizer drugs like Avandia, Actos, and Glucophage, or by adding a drug
"Really, what is most clinically relevant is the comparison of Avandia vs. Actos in the same study," Graham said. In a paper published online
Subjects were randomized to monotherapy with pioglitazone or rosiglitazone after a 4-week placebo washout period. During this time, an
While Actos appears to have a reduced effect compared to Avandia, which was found to lower blood glucose by around 1.5%, base HbA1c
This latest 33-month study, involving over 36000 patients aged 54 years ( average) and 14 months treatment on Actos or Avandia found that:
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The analysis in the journal Diabetes Care projected that one in every 50 patients who takes Avandia or Actos over a 26-month period would be
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Researchers looked at more than 36000 diabetes patients using either Avandia or Actos. Of those who took Avandia, 602 either had a heart
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And lastly, thiazolidinediones (such as Avandia, or rosiglitazone, and Actos, or pioglitazone), which increase the body's sensitivity to insulin.
(troglitazone), Actos (pioglitazone) and Avandia (rosiglitazone) have . The observed delta was compared to the 90% prediction interval from the 100 identical
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Diabetes is a disease in which the body does not produce or properly use insulin. Insulin is a hormone that is needed to convert sugar, starches and other food
We have initially noted that women who conceive following metformin, Actos or Avandia therapy have an unacceptably high (>30%) risk of miscarriage.
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GlaxoSmithKline's fallen diabetes drug Avandia has taken another hit for cardiovascular events with Avandia versus Actos, others have not,
Another TZD, pioglitazone (Actos-Takeda) is also available. For patients treated with rosiglitazone compared to the control group (which included placebo or
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>Why would Metformin be prescribed instead of Actos or Avandia?< >My primary care doc says that actos or avandia would be the way to go
The conclusion of the votes confirmed that Avandia versus other drugs in the saw a heart attack concern versus the drug Actos, specifically.
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The strengthened warning advises health care professionals to be vigilant in checking for signs of heart failure in their Type 2 patients taking Avandia or similar
I use both TZDs, Actos and Avandia, and I think each of them has a niche, and despite the current controversy or issue surrounding Avandia, I do believe that it's
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Contrary to previous papers that showed diabetes the drug Avandia ( rosiglitazone) causing more heart problems than its chief rival Actos
Blood Sugar 101 does not control which products appear in Google Ads or endorse Actos (pioglitazone), Same as Avandia, Reduces insulin resistance, From
Its aim is to test the cardiovascular safety of Avandia versus another leading diabetes drug Actos from Takeda Pharmaceutical Co. Other Indian
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You should not exploit Actos if you are allergic to pioglitazone, if you experience cruel sensibility insolvency, or if you are in a style of diabetic
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Diabetes split could shake up market. Actos-versus-Avandia dynamic could change next year, as Takeda takes on full responsibility. June 24
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Another study was done more recently that analyzed nearly 29000 patient records of those who took either Avandia or Actos from 2001 to 2005. After adjusting
More deaths, heart failure, heart attacks and strokes have occured in patients taking the diabetes drug Avandia vs those taking Actos. Learn more.
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You can enter either the generic or brand name of the drug, but you have to spell it Avandia is a treatment for type 2 diabetes developed by GlaxoSmithKline that Actos was approved by the U.S. Food and Drug Administration in July 1999.
Hadrian, Both are useful drugs. The marketing hype from them is as follows: Actos claims superior lipid lowering. Avandia claims it lowers the more harmful small
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Q: Avandia or Actos, raises blood glucose readings? Has anybody else had Avandia, Actos or another med raise your blood glucose levels, instead of lowering
Compared to patients never having taken Actos, taking Actos for longer heart failure or death in 28938 patients taking Actos or Avandia from
En la actualidad alrededor de 1 millón de pacientes en USA están siendo tratados con Avandia® y un número similar con Actos®. Las ventas
other oral diabetes medications, especially acarbose (Precose), metformin ( Glucophage), miglitol (Glyset), pioglitazone (Actos), or rosiglitazone
GSK complied and is rolling out Avandia with suggested restriction. provider, have decided not to take pioglitazone (Actos) for medical reasons.” high rates of MI in patients taking rosiglitazone versus placebo or another
b Low dose was 2 or 4 mg/day for rosiglitazone and 15 or 30 mg/day for pioglitazone. .. Pioglitazone HCl (marketed as Actos, Actoplus Met, and Duetact ).
to its competitive product Actos, made by Takeda Pharmaceuticals.
2 v/v glutaraldehyde was used. We therefore selected avandia xylose as an acceptor model for transfructosylation reactions. 0 after 38 h of immobilization.
use of Avandia or Actos as initial monotherapy in diabetic patients. Clearly, what is necessary is a biochemical or clinical screening parameter that will
heart attack or stroke, unlike its beleaguered chief rival Avandia,
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Actos has been known to bring edema on or worsen pre-existing edema. Actos and its counterpart GlaxoSmithKline PLC's Avandia, long
there is excess hair growth or other evidence of increased male hormone . Actos and Avandia are only used when using Glucophage is not an option.
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Avandia had negative effects and actos actually had positive effects. Not sure though, can't find the therapeutics notes….. Like or Dislike:
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just can't quite understand if this warning is just for avandia…or does it apply to actos too?? March 12, 2010 at 2:40 pm. (7) Wilma Cook says:
Rosenblatt SI, Yoder CL, Albert JE: Actos vs. Avandia: comparison of conversion from Rezulin on significant clinical parameters (Abstract). Diabetes 51 (Suppl.
The agreement is believed to be the first settlement of Avandia injury is looking at the side effects of Avandia compared to those of Actos,
Rosenblatt SI, Yoder CL, Albert JE: Actos vs. Avandia: comparison of conversion from Rezulin on significant clinical pa- rameters (Abstract). Diabetes 51 (Suppl.
Avandia Vs. Actos. Avandia and Actos are both medications used to treat type 2 diabetes, a condition in which the body doesn't respond
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